West Valley 48, East Valley 33: Collin Sather scored 17 points, Cletis Hydrick added 13 and the No. 2 seed Eagles (13-7) eliminated the visiting fifth-seeded Knights (3-16).
Tyrell Brown and Christian Johnson led East Valley with 10 points apiece.
West Valley will host Cheney in the district semifinal on Saturday.
Cheney 53, Clarkston 50: Devin Cook scored 14 points and the visiting fourth-seeded Blackhawks (9-12) dug themselves out of a 15-0 first quarter hole to eliminate the No. 3 seed Bantams (9-11) in a District 7 2A first round matchup on Wednesday.
Gus Hagstead scored 19 points and Tru Allen added 15 for Clarkston.